Rosiglitazone is one of a newer class of oral glucose-lowering drugs available in the UK. It is currently licensed for use in people whose type 2 diabetes is not controlled by lifestyle measures and other diabetes drugs.
In the long run, solving the challenges that the Summit laid out (PK, permeability, oral bioavailability, and binding modes) will be key to this class delivering the big therapeutic impact we all hope to witness.
The lawyer representing Wal-Mart worker Betty Dukes and perhaps 1.5 million other present and former female Wal-Mart employees was assailed from the right and the left in oral arguments before the Supreme Court today, raising serious questions about whether the huge class action will survive.